Brain Recovery Centers provides FDA-approved Spravato (esketamine) treatment in our clinic for adults whose depression hasn't responded to antidepressants. Often covered by insurance, including MO HealthNet, once prior authorization and plan participation are confirmed.
"Treatment-resistant" describes the medications. It has never described you.
About one in three people with depression don't get better on standard antidepressants. For them, medicine has a real next step now - it just works on a different system in the brain than every pill you've already tried.
FDA-approved for treatment-resistant depression. You take it in our clinic, rest in a comfortable chair while we monitor you for two hours, and someone drives you home - no driving until the next day, after a restful sleep. Covered by most commercial plans, MO HealthNet, TRICARE, and Medicare - we verify your exact cost before your first visit.
How Spravato works →The screener asks what you've tried, how you'd pay, and how you're doing. It routes you to the right program - or tells you plainly if you don't qualify yet, and what would change that.
Coverage verification, prior authorization, denials, appeals - ours to fight, not yours. In published data most appealed denials in this category get overturned; almost nobody files the appeal. We file it. You never chase a fax.
Supervised visits on a set schedule, symptoms measured every time. Most people know where they stand within the first month - not the first year.
Six to eight weeks per antidepressant trial. Multiplied by every medication you've already tried.
Esketamine works on glutamate - a different system entirely. When it works, people tend to feel it in days to weeks.
In our own survey of 443 Midwest adults, commercial insurance and Medicaid came out nearly tied: 39 percent and 37 percent. Most clinics build around one or the other. We built for both.

Most people trust their own physician more than any ad - as they should. So we made this easy to bring to yours: a one-page letter that explains the treatment, the criteria, and how we report progress back.

A national ketamine app can shut down with an email. A clinic in your county can't - and won't.
Brain Recovery Centers is locally owned. Doors you can walk up to, a front desk that answers, and clinicians who live where you live.
Brain Recovery Centers treats patients across St. Charles County and St. Louis County, in person and by telemedicine. Patients are seen at our South County clinic in St. Louis; our headquarters in Chesterfield is an administrative office with no patient visits. Whether you're coming from St. Charles County or from anywhere on the St. Louis side, you're in the right place.
No pressure, no waitlist games. Answer honestly and the screener does the same.
Start the 2-minute screenerBook a consultThe clinic opens October 1, 2026 - we are booking consults now. A real person calls you back within one business day.